Start Date

End Date

Treatment

Result

2003 Dec 22

2004 Jan 20

Thalidomide 50 mg daily

Serum Lambda FLC reduced, Kappa increased, bad rash

2004 Jan 22

2004 Feb 18

Thalidomide 50 mg daily

Serum Lambda FLC reduced more, but more symptoms

2004 Feb 25

2004 Mar 24

Thalidomide 50 mg daily

Serum Lambda FLC almost normal, still more symptoms

2006 Dec 11

2007 Jan 07

Thalidomide 50 mg daily

Serum Lambda FLC reduced? SPEP not reduced

2007 Jan 22

2007 Feb 19

Thalidomide 50 mg daily

SPEP reduced but not much else

2007 Mar 06

2007 Apr 16

Thalidomide 50 mg daily

Serum Lambda FLC reduces, all others increasing Thalidomide is no longer a useful treatment.

2007 Jun 27

2007 Sep 06

Curcumin 8000 mg daily

No clear benefit detected. Sigh

2007 Sep 07

2007 Oct 17

Curcumin 14 g + LDN

IgG down 13% in five weeks. That’s good, hope it holds

2007 Oct 18

2007 Dec 26

Curcumin + LDN + diet

IgG back up, looks like it didn’t hold

2008 Jan 03

2008 Mar 03

Supplements + LDN + diet

IgG stable, M-spike up, PET scan shows bone lesions

2008 Mar 07

2008 Apr 03

CC-4047 + dex + supplmts

IgG down 25%, M-spike down 30%. So far so good

2008 Apr 06

2008 May 03

CC-4047 + dex + supplmts

IgG down 46%, M-spike down 48%. Excellent

2008 May 04

2008 May 31

CC-4047 + dex + supplmts

IgG down 57%, M-spike down 56%. Excellent

2008 Jun 01

2008 Jun 28

CC-4047 + dex + supplmts

IgG up slightly, M-spike down slightly. Hmmm

2008 Jun 29

2008 Jul 26

CC-4047 + dex + supplmts

IgG down slightly, M-spike unchanged. Sigh

2008 Jul 27

2008 Aug 23

CC-4047 + dex + supplmts

IgG down 23%, M-spike down 9%. I’ll take it

2008 Aug 24

2008 Sep 20

CC-4047 + dex + supplmts

IgG up a bit, M-spike stable, Lambda FLC’s at lowest ever

2008 Sep 21

2008 Oct 18

CC-4047 + dex + supplmts

M-Spike down 10% to 0.9, IgG & FLC’s almost unchanged

2008 Oct 19

2008 Nov 15

CC-4047 + dex

M-Spike at 0.97, IgG & FLC’s almost unchanged

2008 Nov 16

2008 Dec 13

CC-4047 + dex + supplmts

M-Spike 1.0, IgG & FLC’s altered by stomach flu episode

2008 Dec 14

2009 Jan 10

CC-4047 + dex + supplmts

M-Spike 1.1, IgG up slightly, FLC’s down slightly

2009 Jan 11

2009 Feb 07

CC-4047 + dex

M-Spike 1.0, IgG back down, FLC’s mostly unchanged

2009 Feb 08

2009 Mar 07

CC-4047 + dex + supplmts

M-Spike 0.9, IgG down more, FLC’s unchanged

2009 Mar 08

2009 Apr 04

CC-4047 + dex + supplmts

M-Spike 0.9, IgG up slightly, FLC’s up slightly

2009 Apr 05

2009 May 02

CC-4047 + dex + supplmts

M-Spike 0.8, IgG unchanged, FLC’s down a bit

2009 May 03

2009 May 30

CC-4047 + dex + supplmts

M-Spike 0.9, IgG & FLC’s unchanged, some neuropathy?

2009 Jun 01

2009 Jun 27

CC-4047 + dex + supplmts

M-Spike 0.9, IgG & FLC’s unchanged, definite neuropathy